Medical Research Division, Edinburg
Photo of Heather L. P. Klug, PhD, MPH

Heather L. P. Klug, PhD, MPH

Technical Director, Research Core Facility

Flow Cytometry Core

Office # 2.104
956-393-6456
Email: klug@uthscsa.edu

Laboratory # 2.330
956-393-6446

Keywords

Cancer, Cancer Prevention, Immunology, Immune Function, Melanoma, HPV, Cervical Cancer, Public Health, Flow Cytometry

Specialization and Research Interests

Dr. Klug is an immunologist and cancer biologist with specialized training in cancer prevention and public health. Dr. Klug's research goals are to examine the interactions of immune function and cancer development, particularly in infection-related cancers, and to translate this research into practical applications ultimately benefiting human health. She is interested in collaborative research studies in human populations and public health while maintaining the use of animal models to enhance a translational research program. Animal models of cancer, including the HGF/SF transgenic mouse model of UV-induced human melanoma, are of interest. Dr. Klug's areas of expertise and research on immune competence have broad relevance and applications to other cancers, other chronic diseases, and to the increased disease susceptibility seen with human aging.

Professional Memberships/Activities

  • American Association for Cancer Research, current member
    • AACR-Women in Cancer Research
    • AACR-Minorities in Cancer Research
  • AACR-Molecular Epidemiology Working Group
  • American Association of Immunologists, current member
  • American Public Health Association, current member

Honors and Awards

  • 2000-2003 Cancer Prevention Fellow, Cancer Prevention Fellowship Program, Div. of Cancer Prevention, National Cancer Institute
  • 2006 Scholarship of Community Engagement Award, The Center for Civic Engagement, UT Brownsville
  • 2006 American Association for Cancer Research-Minority Serving Institution Faculty Scholar Awards in Cancer Research, 97th Annual Meeting

Selected Publications

Klug, H. L. P., Tooze, J. A., Graff-Cherry, C., Anver, M. R., Noonan, F. P., Fears, T. R., Tucker, M. A., De Fabo, E. C. and Merlino, G. 2010. Sunscreen prevention of melanoma in man and mouse. Pigment Cell & Melanoma Research, 23(6):835–837. doi:10.1111/j.1755-148X.2010.00756.x
[PMID: 20726949]
Selected by Editor for Cover bi-line and as SciVeeTM Pubcast http://www.scivee.tv/node/17730.

Benavides, F., Venables, A.**, Poetschke Klug, H., Glasscock, E., Rudensky, A., Gomez, M., Martin Palenzuela, N., Guenet, J-L., Richie, E.R., Conti, C.J., 2001. The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (Ctsl) gene. Immunogenetics 53:233-242
[PMID: 13398968]

Poetschke, H.L., Klug, D.B., Perkins, S., Wang, T.T.Y., Richie, E.R., and Hursting, S.D., 2000. The Effects of Calorie Restriction on Thymocyte Growth, Death and Maturation. Carcinogenesis 21(11): 1959-1964.
[PMID: 11062154]

Poetschke, H.L., Klug, D.B., Walker, D., and Richie, E.R. 1996. Cross-Linking the TCR Complex Induces Apoptosis in CD4+8+ Thymocytes in the Presence of Cyclosporin A. Developmental Immunology 5: 1-15.
[PMID: 8828007]

Georgiou, G., Stephens, D.L., Stathopoulos, C., Poetschke, H.L., Mendenhall, J., and Earhart, C.F. 1996. Display of -lactamase on the Escherichia coli Surface: Outer Membrane Phenotypes Conferred by Lpp'-OmpA'--lactamase Fusions. Protein Engineering 9(2):239-247.
[PMID: 9005446]

Georgiou, G., Poetschke, H.L., Stathopoulos, C., and Francisco, J.A. 1993. Practical Applications of Engineering Gram-negative Bacterial Cell Surfaces. Trends in Biotechnology 11: 6-10.
[PMID: 7763382]

**Mentored graduate students